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In Oceania at the present day, Science, in the old sense, has almost ceased to exist. In Newspeak there is no word for "Science." The empirical method of thought, on which all the scientific achievements of the past were founded, is opposed to the most fundamental principles of Ingsoc. And even technological progress only happens when its products can in some way be used for the diminution of human liberty. (2.9.30).
The Party employs science and technology to curtail human freedom and privacy, and to control human behavior.
In principle, membership of these three groups is not hereditary. The child of Inner Party parents is in theory not born into the Inner Party. Admission to either branch of the Party is by examination, taken at the age of sixteen. Nor is there any racial discrimination, or any marked domination of one province by another. Jews, Negroes, South Americans of pure Indian blood are to be found in the highest ranks of the Party […] Its rulers are not held together by blood-ties but by adherence to a common doctrine […] The Party is not a class in the old sense of the word. It does not aim at transmitting power to its own children, as such; and if there were no other way of keeping the ablest people at the top, it would be perfectly prepared to recruit an entire new generation from the ranks of the proletariat. In the crucial years, the fact that the Party was not a hereditary body did a great deal to neutralize opposition […] The essence of oligarchic rule is not father-to-son inheritance, but the persistence of a certain world-view and a certain way of life, imposed by the dead upon the living. A ruling group is a ruling group so long as it can nominate its successors. The Party is not concerned with perpetuating its blood but with perpetuating itself. (2.9.58, Goldstein’s Manifesto)
The Party’s view of loyalty is that for totalitarianism to thrive, there must not be private loyalties at all. Rather, insofar as Inner Party members are concerned with the perpetuation of the Party’s rule, the only allowable loyalty is the loyalty to power itself.