There are many betrayals throughout Angels in America. Louis betrays his lover, Prior, by deserting him at a time of need. Roy feels betrayed when Joe refuses to take a job he's arranged for him in Washington, DC. Of course Joe might very well feel betrayed when he learns that Roy wants him to take the job for his own selfish reasons. And then there's Harper, who feels betrayed when her husband, Joe, admits that he's gay. Very often throughout the play we are left asking, "Which is worse: betraying another or betraying yourself?"
Fear is an emotion all characters in Angels in America share, and it is always fear that drives them to betray those whom they love.
Betrayal is not always a bad thing. Throughout the play characters turn their backs on ideas that have made their lives unhappy.