You created the cure for cancer! Unfortunately, six months after taking the miracle drug, everyone who tried it grows a second head. We're afraid you're in a bit of trouble.
You teach high school chemistry. Sandra in the second row is wondering if she might have any with you. Better steer clear of that one.
You work for a small manufacturing company, testing various materials and making recommendations for improvement. They wanted to make a better car tire; instead they made flubber. It's ai-ight.
You work for a major pharmaceutical company, and are assigned to a team attempting to design a completely effective baldness reversal drug. While it will be great if you're successful, hair will still not cancel out some people's ugly.
Working independently with financial backing, you personally found a cure for Alzheimer's. No one will ever forget what you have done, not even old people.