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Had I right, for my own benefit, to inflict this curse upon everlasting generations? I had before been moved by the sophisms of the being I had created; I had been struck senseless by his fiendish threats; but now, for the first time, the wickedness of my promise burst upon me; I shuddered to think that future ages might curse me as their pest, whose selfishness had not hesitated to buy its own peace at the price, perhaps, of the existence of the whole human race. (20.1)
Victor realizes that he must go back on his promise in order to protect humanity from the monster he inadvertently created. He realizes he must give up his own safety and desires in order to protect humanity from the dangers of his intellectual exploration.
"Shall each man," cried he, "find a wife for his bosom, and each beast have his mate, and I be alone? I had feelings of affection, and they were requited by detestation and scorn. Man! You may hate, but beware! Your hours will pass in dread and misery, and soon the bolt will fall which must ravish from you your happiness forever. Are you to be happy while I grovel in the intensity of my wretchedness? You can blast my other passions, but revenge remains -- revenge, henceforth dearer than light or food! I may die, but first you, my tyrant and tormentor, shall curse the sun that gazes on your misery. Beware, for I am fearless and therefore powerful. I will watch with the wiliness of a snake, that I may sting with its venom. Man, you shall repent of the injuries you inflict." (20.11)
The monster expresses to Victor that he could lose everything if he goes against the monster’s wishes. But Victor remains steadfastly self-sacrificing, realizing that the danger to the world is larger than the danger to himself. He is forced to self-sacrifice to account for his hasty rush into scientific inquiry.