When it starts off "He Who Has Seen the Deep," you know it's either a really hardcore black metal song … or an ancient Mesopotamian epic. In this case, it's The Epic of Gilgamesh: an ancient Mesopotamian epic about a man who knew everything—the whole enchilada. And then, a few paragraphs in, it become rather obviously that, well, either the Sumerians themselves didn't know much, or this Gilgamesh fella was going to have a serious turn-around before the end of the poem. Thankfully, it's the latter. Gilgamesh's adventures start off as macho-man contests, but develop into searches for wisdom and knowledge. It's comforting to know that even someone as big of a mess-up as Gilgamesh can eventually pull it together.
The Epic of Gilgamesh portrays wisdom and knowledge as two different things. Otherwise, Enkidu would not have unwisely told Gilgamesh to kill Humbaba even though he knew that Enlil had appointed Humbaba as the guardian of the Cedar Forest.
In the Epic of Gilgamesh, wisdom has to come through experience, not just through hearing about it. Otherwise, Gilgamesh would have been convinced by the wise advice that many people gave him.