A big chunk of The Girl With the Dragon Tattoo is set on a remote Swedish island mostly owned and inhabited by the Vanger family. It also features several isolated cabins, a bedroom torture chamber, and a serial killers basement. These isolated settings work with the isolated mindsets of the main characters. Henrik Vanger is shut off from everything by his obsession with Harriet's disappearance. If Blomkvist wasn't isolated by his recent professional disgrace, he would never have jumped on board to help Henrik. Salander is perhaps the most isolated character of all –she's the novel's true outsider. Even Martin has a life full of friends and family who love him. But Salander is isolated from even her friends by her legal status and her lack of trust. We are also asked to feel the isolation of minor characters – Martin's victims, the women who spent their last days and hours in his windowless, soundproof chamber of horrors.