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Lennie cried out suddenly—"I don' like this place, George. This ain't no good place. I wanna get outa here." (2.165)
Out of the mouth of babes: Lennie may not be book-smart (we're not even sure he can read, come to think of it), but he has a kind of gut-instinct that makes him sensitive to bad vibes on the ranch. Too bad George, who's a relative genius compared to Lennie, doesn't listen.
Slim looked through George and beyond him. "Ain't many guys travel around together," he mused. "I don't know why. Maybe ever'body in the whole damn world is scared of each other." (2.179)
If being together is so great, you'd think that more guys would team up. (Also, you always die if you go off alone.) But they don't. Is it more dangerous to be together? In this world, it just might be.
"We travel together," said George coldly.
"Oh, so it's that way."
George was tense and motionless. "Yea, it's that way." (2.80-82)
By saying "Oh, so it's that way," Curley is essentially accusing Lennie and George of being gay. But George doesn't take the bait. It just shows how pathetic Curley is that he can't understand the men's friendship.