One Hundred Years of Solitude is a meditation on the history of an independent Colombia, merging several hundred years of events into an allegorical description of the evolution of Macondo. Pretty impressive feat, we must say. But there's more! At the same time, the novel emphasizes just how prone people are to either willfully or accidentally forgetting their past and their origins, usually with terrible and avoidable consequences. Because it's continuously being lost, time in the novel is cyclical and repetitive, as generation after generation is doomed to either repeat the mistakes of their ancestors or fall into spirals of ineffectual and pointless activity.
Despite the novel's insistence that collective memory loss is tragic, it does serve to protect characters from horrible, life-altering truths they have no control over anyway.
Because the repetitive cycle of time only occurs in Macondo, it's clearly a very specific instance that won't be replicated. So no worries for the rest of us.