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"They have both," said she, "been deceived, I dare say, in some way or other, of which we can form no idea. Interested people have perhaps misrepresented each to the other. It is, in short, impossible for us to conjecture the causes or circumstances which may have alienated them, without actual blame on either side." (17.1-2)
Jane can't believe Wickham's story about Darcy, so she comes up with an explanation: they've been deceived. Unfortunately, they're the ones who are being deceived by that class A liar, Wickham.