Scurry, scurry, scurry. A mouse's work is never done. Mrs. Frisby goes all over trying to make sure her family has enough food.
Timothy gets a cold and Mrs. Frisby gets a panic attack that sends her in search of Mr. Ages, who she hopes can help her save Timothy.
On her way to Mr. Ages' house, she takes the long way to avoid being eaten by Dragon, that big bully. Smart move, Mrs. F.
As she is cruising through the fields to get back to her babies, she hears a bunch of squawking and sees a crow tied up to a fence post by his foot.
Even though she is scared, she goes to help the crow, who introduces himself as Jeremy. When she unties him, he offers to give her a ride home on his back, which gives her the chance to ask his advice about Timothy and the problem with her house.
Not being the smartest guy in the world, Jeremy can't help. But, luckily for Mrs. Frisby, he knows someone who can: he tells her to go to the Owl and flies her there.
Terrified, Mrs. Frisby hops on Jeremy's back and talks to the Owl.
At first he won't help her, but then he learns her last name is Frisby. Whoa! Total about-face. Now he is willing to listen.
Owl tells her to "go to the rats." This sounds like an insult, but really he is just giving her some advice.
Mrs. Frisby, still terrified, does what she is told and goes to visit the rats. At first, they won't let her in.
Eventually, she is permitted inside, where she is amazed by the rats' luxurious living quarters and begins to wonder what their deal is.
The rats agree to help her. However, like the Owl, they only agree to help after they learn that she is a Frisby.
Mrs. Frisby volunteers to put the sleeping potion in Dragon's food dish, but she ends up getting caught by one of the farmer's kids, who puts her in a birdcage and wants to keep her as a pet.
Luckily for the rats, Mrs. Frisby overhears the farmers talking about a group of mysterious exterminators who are coming out to destroy the rats.
Justin arrives to set Mrs. Frisby free and she tells him and Nicodemus about what she heard. This saves the day and allows the rats to figure out a plan to avoid being captured or killed.
The Frisbys live happily ever after and the novel ends with Mrs. Frisby telling her children the story of the Rats of NIMH.