No character in the world of "The Chrysanthemums" seems perfectly content. In the story, a sense of dissatisfaction arises from two main sources: a failure to successfully express oneself, and a failure, on the part of others, to fulfill one's emotional needs. Of course this is connected to the theme of isolation, because the more dissatisfied the characters (to be honest, we're really talking mostly about Elisa) become with their circumstances, the more alone they feel.
Elisa's dissatisfaction is her own fault. Come on, people – she just needs a hobby.
Henry is the root cause for Elisa's lack of fulfillment. In all their interactions, he fails to give her what she needs to be happy.