Every man that isn't Kino or Juan Tomás
We’re talking about the doctor, priest, pearl-buyer, intruders, jealous neighbors, thieves – get the picture? These are all the people who corrupt the pearl, who make it evil because of their greed. That’s why we didn’t call the pearl itself the antagonist, although that may be the temptation. All the misery that Kino suffers is the result of people trying to screw him over so they can have his treasure for themselves.