As Donkey said before he and Shrek became friends, "I'm all alone, there's no one here beside me." Humans spend a lot of time trying to feel less lonely—why else would sites like Match.com and eHarmony exist? Unfortunately, there's no dating site for Gods (that we know of). And there's no after church coffee hour for Bob, either. So how is he supposed to reach out and connect? (Don't say Facebook.)
Power is the greatest isolating force in There Is No Dog.
In this novel, love rather than friendship is the cure to isolation.