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She's Come Undone is a story of transformation, but not a supernatural one. Dolores doesn't turn into a werewolf or vampire or golem or anything—instead she gets depressed, she overeats, and she transforms into a very heavy version of herself. Dolores doesn't transform instantly, like Optimus Prime from a truck into a robot. Her transformation is slow, as she grows to over two hundred and fifty pounds and then shrinks back down again. And it isn't just physical either. She's depressed, so she eats, then she's fat, so she's depressed. It's a vicious cycle that is hard to break.
Dolores embraces her transformation and uses it as an excuse to be mean to people: It's not her talking, it's the fat girl.
More than any other shift, Dolores's biggest transformation is from victim to someone in control of her life.