Macro Risk
  
See: Macro Environment. See: Macro Manager.
When you take macro risk, you're accepting the risks of the world's "bigger stuff." Things like global interest rate changes (all of our systems are pretty tightly linked), war, pestilence, boils, locusts, currency value declines...all macro risks.
If your name is Moses, maybe you have a leg (or staff) up on the rest of us. But you'll still need to consult with your mentor before you place your bets.