Your country lies desolate, your cities are burned with fire; in your very presence aliens devour your land; it is desolate, as overthrown by foreigners. And daughter Zion is left like a booth in a vineyard, like a shelter in a cucumber field, like a besieged city. If the Lord of hosts had not left us a few survivors, we would have been like Sodom, and become like Gomorrah. (NRSV 1:7-9)
Our country is desolate, your cities are burned with fire: your land, strangers devour it in your presence, and it is desolate, as overthrown by strangers. And the daughter of Zion is left as a cottage in a vineyard, as a lodge in a garden of cucumbers, as a besieged city. Except the Lord of hosts had left unto us a very small remnant, we should have been as Sodom, and we should have been like unto Gomorrah. (KJV 1:7-9)
Here, suffering takes the form of being totally exposed and vulnerable—open to any outside forces that want to come by and claim or abuse you. Not fun.
Dibon has gone up to the temple, to the high places to weep; over Nebo and over Medeba Moab wails. On every head is baldness, every beard is shorn; in the streets they bind on sackcloth; on the housetops and in the squares everyone wails and melts in tears. Heshbon and Elealeh cry out, their voices are heard as far as Jahaz; therefore the loins of Moab quiver; his soul trembles. My heart cries out for Moab; his fugitives flee to Zoar, to Eglath-shelishiyah. For at the ascent of Luhith they go up weeping; on the road to Horonaim they raise a cry of destruction. (NRSV 15:2-5)
He is gone up to Bajith, and to Dibon, the high places, to weep: Moab shall howl over Nebo, and over Medeba: on all their heads shall be baldness, and every beard cut off. In their streets they shall gird themselves with sackcloth: on the tops of their houses, and in their streets, every one shall howl, weeping abundantly. And Heshbon shall cry, and Elealeh: their voice shall be heard even unto Jahaz: therefore the armed soldiers of Moab shall cry out; his life shall be grievous unto him. My heart shall cry out for Moab; his fugitives shall flee unto Zoar, an heifer of three years old: for by the mounting up of Luhith with weeping shall they go it up; for in the way of Horonaim they shall raise up a cry of destruction. (KJV 15:2-5)
Isaiah himself is upset about the suffering Moab has to undergo. The people here are, again, stripped of their protection—not to mention their beards and clothing. Suffering here too is a position of total vulnerability.
The princes of Zoan have become fools, and the princes of Memphis are deluded; those who are the cornerstones of its tribes have led Egypt astray. The Lord has poured into them a spirit of confusion; and they have made Egypt stagger in all its doings as a drunkard staggers around in vomit. Neither head nor tail, palm branch or reed, will be able to do anything for Egypt. (NRSV 19:13-15)
The princes of Zoan are become fools, the princes of Noph are deceived; they have also seduced Egypt, even they that are the stay of the tribes thereof. The Lord hath mingled a perverse spirit in the midst thereof: and they have caused Egypt to err in every work thereof, as a drunken man staggereth in his vomit. Neither shall there be any work for Egypt, which the head or tail, branch or rush, may do. (KJV 19:13-15)
Here suffering takes the form of being possessed by a "spirit of confusion," the opposite of God's creative, positive spirit. It's similar to what the Talmud calls the "wind of idiocy" (great name, right?). Instead of carrying you towards God, it's a wind or spirit that carries you away.
Dill is not threshed with a threshing sledge, nor is a cart wheel rolled over cumin; but dill is beaten out with a stick, and cumin with a rod. Grain is crushed for bread, but one does not thresh it forever; one drives the cart wheel and horses over it, but does not pulverize it. This also comes from the Lord of hosts; he is wonderful in counsel, and excellent in wisdom. (NRSV 28:27-29)
For the fitches are not threshed with a threshing instrument, neither is a cart wheel turned about upon the cumin; but the fitches are beaten out with a staff, and the cumin with a rod. Bread corn is bruised; because he will not ever be threshing it, nor break it with the wheel of his cart, nor bruise it with his horsemen. This also cometh forth from the Lord of hosts, which is wonderful in counsel, and excellent in working. (KJV 28:27-29)
Suffering takes on a new meaning in this quote. It isn't just a result of God punishing people. It's a process that, by crushing the people, allows them to grow into something far greater.
A voice says, "Cry out!" And I said, "What shall I cry?" All people are grass, their constancy is like the flower of the field. The grass withers, the flower fades, when the breath of the Lord blows upon it; surely the people are grass. The grass withers, the flower fades; but the word of our God will stand forever. Get you up to a high mountain, O Zion, herald of good tidings; lift up your voice with strength, O Jerusalem, herald of good tidings, lift it up, do not fear; say to the cities of Judah, "Here is your God!" (NRSV 40:6-9)
The voice said, Cry. And he said, What shall I cry? All flesh is grass, and all the goodliness thereof is as the flower of the field: The grass withereth, the flower fadeth: because the spirit of the Lord bloweth upon it: surely the people is grass. The grass withereth, the flower fadeth: but the word of our God shall stand for ever. O Zion, that bringest good tidings, get thee up into the high mountain; O Jerusalem, that bringest good tidings, lift up thy voice with strength; lift it up, be not afraid; say unto the cities of Judah, Behold your God! (KJV 40:6-9)
This implies that suffering is caused by change, the way everything decays and disappears as time goes on. But since God is beyond change, Isaiah suggests that one remedy to this problem would be to turn your attention toward him.
Therefore justice is far from us, and righteousness does not reach us; we wait for light, and lo! there is darkness; and for brightness, but we walk in gloom. We grope like the blind along a wall, groping like those who have no eyes; we stumble at noon as in the twilight, among the vigorous as though we were dead. We all growl like bears; like doves we moan mournfully. We wait for justice, but there is none; for salvation, but it is far from us. For our transgressions before you are many, and our sins testify against us. Our transgressions indeed are with us, and we know our iniquities: transgressing, and denying the Lord, and turning away from following our God, talking oppression and revolt, conceiving lying words and uttering them from the heart. Justice is turned back, and righteousness stands at a distance; for truth stumbles in the public square, and uprightness cannot enter. Truth is lacking, and whoever turns from evil is despoiled. The Lord saw it, and it displeased him that there was no justice. (NRSV 59:9-15)
Therefore is judgment far from us, neither doth justice overtake us: we wait for light, but behold obscurity; for brightness, but we walk in darkness. We grope for the wall like the blind, and we grope as if we had no eyes: we stumble at noon day as in the night; we are in desolate places as dead men. We roar all like bears, and mourn sore like doves: we look for judgment, but there is none; for salvation, but it is far off from us. For our transgressions are multiplied before thee, and our sins testify against us: for our transgressions are with us; and as for our iniquities, we know them; In transgressing and lying against the Lord, and departing away from our God, speaking oppression and revolt, conceiving and uttering from the heart words of falsehood. And judgment is turned away backward, and justice standeth afar off: for truth is fallen in the street, and equity cannot enter. Yea, truth faileth; and he that departeth from evil maketh himself a prey: and the Lord saw it, and it displeased him that there was no judgment. (KJV 59:9-15)
Suffering is the same as being lost in total darkness, groping around for some sort of support that you're probably not going to find. The metaphor from the Gospels describes it too: "gnashing of teeth" in "outer darkness."