How we cite our quotes: (Sentence)
Quote #1
When in the Course of human events, it becomes necessary for one people to dissolve the political bands which have connected them with another... they should declare the causes which impel them to the separation. (1)
Yep, this is very first sentence, and it might not seem like it's blaring the trumpet of dissatisfaction. This sentence is key for establishing a very important idea though—that independence is "necessary." Why is it necessary? Well, he goes on to explain all that, but the overarching theme is dissatisfaction with the current government, to such an extent that the colonies literally must separate themselves.
Quote #2
But when a long train of abuses and usurpations, pursuing invariably the same Object evinces a design to reduce them under absolute Despotism, it is their right, it is their duty, to throw off such Government, and to provide new Guards for their future security. (6)
Clearly Jefferson (and company) is not terribly happy with the government he's describing here. He accuses that government of abuse and acting against the people's interest, suggesting that a new government by the colonists' hand will do much better. Generally speaking, people, especially those who are used to fairly lax government, don't appreciate being taken over by a tyrannical one. To each his own, of course, but history generally shows us that despotism doesn't go over well with the public.
Quote #3
He has called together legislative bodies at places unusual, uncomfortable, and distant from the depository of their public Records, for the sole purpose of fatiguing them into compliance with his measures. (13)
The long list of abuses that Jefferson provides is all evidence and reason for the colonists' dissatisfaction with the British government. This line feels less like an accusation, and more like pure annoyance with King George III. What is Jefferson really accusing the British government of here, besides the specific action he describes? What does this particular action say about the relationship between the King and the colonies?