And If I couldn't find a niche in a school with three thousand people, what were my chances here? (1.61.3)
At her large school in Phoenix, Bella always felt like an outsider. If she couldn't find any friends there, how will she in tiny Forks? Why do you think it is that Bella doesn't fit in? Is she's simply born to be among vampires instead of humans?
I felt a surge of pity and relief. Pity because, as beautiful as they were, they were outsiders, clearly not accepted. Relief that I wasn't the only newcomer here, and certainly not the most interesting by any standard. (1.138)
Bella feels instant alignment with the Cullen family because of they have isolation in common.
It seemed excess for them to have both looks and money. But as far as I could tell, life worked that way most of the time. It didn't look as if it bought them any acceptance here. (2.12)
According to Bella, money does not buy acceptance, and neither does attractiveness, as evidenced by the Cullen kids. However, Bella seems to be assuming that the Cullens want to fit in. Do you think that's the case? Could they fit in if that's what they wanted?
Driving to school, I distracted myself from my fear of falling and my unwanted speculations about Edward Cullen by thinking about Mike and Eric, and the obvious difference in how teenage boys responded to me here. I was sure I looked exactly the same as I had in Phoenix…Maybe it was just that the boys back home had watched me pass through all the awkward phases of adolescence and still thought of me that way. Perhaps it was because I was a novelty here, where novelties were few and far between. Possibly my crippling clumsiness was seen as endearing rather than pathetic, casting me as a damsel in distress. Whatever the reason, Mike's puppy dog behavior and Eric's apparent rivalry with him were disconcerting." I wasn't sure if I didn't prefer being ignored. (3.9)
Bella speculates on why the boys in Forks are interested in her, given that she was ignored back in Phoenix. She seems to find the attention unwelcome. Is that because she truly likes being ignored, or because she's not interested in Mike and Eric? After all, it seems that she wants to be noticed by Edward.
[Bella to Edward:] "My mind doesn't work right? I'm a freak?" The words bothered me much more than they should – probably because his speculation hit home. I'd always suspected as much, and it embarrassed me to have it confirmed. (9.18)
Edward thinks himself strange because he can read minds, but Bella is the one who feels isolated because he can't hear her voice. Here, we have two people, who have previously felt lonely and isolated, coming together.
[Bella to Charlie:] "Dad, you're doing a great job." I smiled, hoping my relief didn't show. "I've never minded being alone – I'm too much like you." (12.63)
Rather than feeling isolated and lonely, Bella seems to enjoy alone time, a personality trait that she has inherited from her father.
[Edward to Bella:] "Well…." He contemplated for a moment. "It was just how close you were. Most human instinctively shy away from us, are repelled by our alienness…I wasn't expecting you to come so close… And the smell of your throat." He stopped short, looking to see if he'd upset me. (13.140)
Despite vampires being attractive in many ways, most humans separate themselves from the vampires out of instinctual fear. Yet, Bella is naturally drawn to Edward. What does that say about her?
[Edward to Bella:] His soft voice interrupted my thoughts. "[Carlisle] acted from loneliness. That's usually the reason behind the choice. I was the first in Carlisle's family, thought he found Esme soon after. She fell from a cliff. They brought her straight to the hospital morgue, though, somewhere her heart was still beating." (14.20)
Edward is speaking of Carlisle and why he changed/saved the other vampires in his family. It seems like Carlisle changed Edward out of a desire for a companion, rather than out of compassion for Edward.
[Edward to Bella:] "[Carlisle] was studying in Italy when he discovered the others there. They were much more civilized and educated than the wraiths of the London sewers." (16.58)
Edward tells Bella the story of Carlisle's and about the extreme isolation he had felt when he first became a vampire. Carlisle was surprised to find others who were sophisticated like him. However, he remained isolated because of his "vegetarian" diet. Until he created his own family, Carlisle was pretty much alone.
[Alice to Bella:] "It's been almost a century that Edward's been alone. Now he's found you. You can't see the changes that we see, we who have been with him for so long. Do you think any of us want to look into his eyes for the next hundred years if he loses you?" (20.51)
Alice echoes Esme's earlier sentiment that Edward has led a lonely life. Now, the Cullens are willing to fight James in order to ensure Edward's happiness.