We cut back to Deadpool in the present, mid-Colossus-fling. Colossus explains to Deadpool that he and Negasonic Teenage Warhead have come to apprehend both Deadpool and Francis. Deadpool's not into it.
Colossus persists. He wants Deadpool to act like a superhero, do the right thing, and join the X-Men. Deadpool unleashes a tirade of insults aimed at the X-Men that essentially boils down to another big, fat "Nope."
While Deadpool and Colossus go back and forth, we see Francis start removing the sword that, truth be told, really should've killed him by now. Then we hear his motorcycle rev, and he's gone. Deadpool's ticked.
Deadpool tries to take his anger out on Colossus. Each time he hits the imposing man of steel (not that Man of Steel), he injures himself. Badly. By the end of the "fight," Deadpool's suffered a host of badly broken bones and damage joints. Colossus handcuffs Deadpool to himself and drags him away the way a toddler might drag his teddy bear around the living room.
Before Colossus and Negasonic Teenage Warhead can take Deadpool away, presumably to the X-Jet, Deadpool cuts off his own hand and escapes. He dives into a passing garbage truck on the highway below, leaving Colossus holding his self-amputated hand, middle finger outstretched.