Molecular Genetics: Deadly Mutations

In this video from our course on molecular genetics, learn all about deadly mutations.

BiologyMolecular Genetics

Transcript

00:29

you live to about twenty five years old to just

00:32

reproduce And then it would kill you like and so

00:36

some of these things you understand genetically why they exist

00:39

because it let the person replicate But then they passed

00:42

on the bad gene Why do we have bad mutations

00:47

You know that's a great question Why do mutations even

00:49

persist if they're so detrimental in some cases there's Some

00:52

benefit that we might not know that for example sickle

00:54

cell people have one copy One bad copy The genius

00:57

resistant to malaria too Bad copies You're gonna get sickle

01:00

cell anemia In other cases musicians just happened for no

01:04

reason And they're bad It's Not like a weren't selected

01:07

for but you happen to get them through bad luck

01:09

And so you have a disease That was it How

01:12

do we get deadly mutations How does that work Is

01:15

it just kind of a crap shoot in the way

01:20

We were of all yes mutations can arise in a

01:22

couple of ways One is that there are some rice

01:25

which is then time net replicant today And it just

01:27

makes mistakes sometimes it's pretty good but sometimes their mistakes

01:29

that don't get fixed And why does it make a

01:31

mistake Like what would be the cause Or is it

01:33

just there's so many of them Eventually you're gonna have

01:36

someone transcribed the number wrong Yeah i think both of

01:38

those are right So sometimes yeah it has to replicate

01:41

you know billions of nucleotides every time a cell divides

01:44

Also there are certain places where it tends to slip

01:46

So let's say there's a bunch of teas in a

01:48

row it's possible the sunrise We'll lose track and not

01:50

realize what it where it is A kind of slipped

01:52

back and re duplicate that so there's certain hot spots

01:55

of mutations But then also they're totally random at times

01:59

But you could also get mutations externally So from the

02:01

sun we know that you be could damage your skin

02:04

computations tobacco smoke vacation so it can kind of be

02:08

internal or external And the how you cope with that

02:12

I mean certainly different people cope differently But certain mutations

02:15

are going to just one hundred percent cause certain diseases

02:19

So for example if you have a taste expedition you're

02:21

gonna get yeah Why do we have bad mutations How 00:02:30.42 --> [endTime] do we get deadly mutations