Medusa is the name of a character in the universe of Marvel Comics. She's an enemy of the Fantastic Four. She also suffers from amnesia, which we thought was pretty funny (source).

An adult jellyfish is called a medusa (source).

In The Lightning Thief, Percy Jackson ends up beheading Medusa, just like the guy he was named after.

Actress Uma Thurman plays Medusa in the movie version of the Percy Jackson book, The Lightning Thief.

The tale of Perseus is the basis of both of the Clash of Titans films.

There's a town in New York with the oh-so-pleasant name of Medusa.