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U.S. History 1877-Present 9.7: The Technology of War–Penicillin 23 Views


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Description:

If someone told you to rub mold on an infection, you'd probably look at them like they had a second head. Well, the world is a strange place, and one particular kind of fungus has actually saved a lot of lives.

Language:
English Language

Transcript

00:03

Turns out the magic bullet during WWII wasn't what it sounds [bullet onstage]

00:08

like. Instead, one of the major technological advances that likely made

00:11

an Allied victory possible was a fungus: penicillin. Invented, or rather [bullet pulls mushroom out of hat]

00:17

accidentally discovered, by Alexander Fleming in 1928, penicillin was the first [penicillin discovered]

00:22

antibiotic on the market capable of killing other disease-causing

00:26

microorganisms. It was a great day for humanity and a bad day for microorganisms.

00:32

Fleming published his work, but he wasn't able to produce penicillin in mass [microorganisms despair]

00:36

quantities. So the scientific world mostly forgot about his discovery... yeah,

00:40

great going there, guys. Then, World War II came along and people started [World War II photos]

00:44

thinking it would be mighty nice if they had some way to fight infection on the

00:48

battlefield. Well, British scientists picked up Fleming's research and came up [scientists recreate penicillin]

00:52

with a penicillin injection, but they weren't able to produce it on a large

00:56

enough scale for it to make a difference. So, British scientists snuck some of the

01:00

wonder mold over to America to take advantage of America's larger laboratory [mold goes west]

01:05

infrastructure to get Allied production of penicillin up and running. With a little

01:09

poking and prodding by the government, pharmaceutical companies eventually

01:12

decided to do their part, and penicillin production skyrocketed from 21 billion

01:17

units in 1943 to 1663 billion units in 1944, to over 6 trillion units in 1945. And [penicillin growth chart]

01:28

just like, that a miracle drug flooded the market. Yes, it was a flood of mold...

01:33

but in this case, the mold was a good thing. The impact of penicillin on the

01:37

war and the world can't be overstated. In one fell swoop, thousands of battlefield [penicillin ads]

01:41

infections were stopped in their tracks, and since, you know, like the dawn of

01:45

time, people have been dying of infections in one way or another that we

01:49

don't even pay attention to today. One little scrape that got infected killed

01:53

the healthiest people, and just imagine how many soldiers died over the century [people dying of infection]

01:58

from wounds. Well, don't imagine their infected wounds, though. That's just too

02:02

gross. Some estimate that penicillin saved 3,000 lives at the Battle of Normandy

02:07

alone. Its super antibiotic powers kept soldiers from dying from the evils of [Normandy picture]

02:12

gangrene, which is an infection that basically rots you to

02:15

death. Yep, feel free to gag now. In the end, maybe it wasn't entirely fair to [gangrene diagram... look away]

02:19

call penicillin World War II's magic bullet. It was more like the magic anti-

02:24

bullet-related-infection drug, but that's less catchy. [penicillin speaks]

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