The awesome actor Ralph Fiennes (a.k.a. Voldemort) played Hades in the 2010 remake of Clash of Titans.

The dwarf planet Pluto, which used to be considered a regular planet, is named after Hades's Roman counterpart.

Mickey Mouse's dog, Pluto, is most likely named after the former planet Pluto, and not the lord of the dead.

In the Harry Potter series, Hagrid's giant, three-headed dog Fluffy was probably inspired by Hades's three-headed guard dog Cerberus.