You will be poked. You will be pushed, bitten, hit, and your hair will get pulled. You'll be pinched, grabbed and you'll trip over a lot of little things. And you're in real danger of getting hugged. A lot.
Seriously, you should be strong enough to lift 40 to 50 pounds, which weighs a lot more when it's asleep and twice as much when it's swinging its arms and legs around and trying to get out of its clothes.
You must (by law) be up-to-date on your vaccinations, but you'll still be a good candidate for catching whatever your kids have.