George and Lennie spend the night by the Salinas River in northern California. They argue over Lennie’s mouse and obsession with soft things, and discuss their dreams of a farm they can own.
George reminds Lennie to come back to this exact spot if he does something "bad."
George takes Lennie to the new ranch near Soledad, California after they flee their last job in Weed, where Lennie caused his usual type of trouble – that is, petting.
George warns Lennie not to talk to Curley, Curley’s wife, or the boss. In other words, Lennie is to keep his big mouth shut around everyone.
George gets one of Slim’s puppies for Lennie.
George tells Slim about the girl in Weed.
He recounts the farm-dream story to Lennie.
George agrees that Candy can join them in their future ranch endeavor if he contributes three hundred dollars.
George tells Lennie to fight back when Curley attacks him.
George goes to the (cheap and clean-ish) local whorehouse.
George comes back and discovers that Crooks now knows about the dream farm.
George plays horseshoes with all the other men except for Lennie, who’s in the barn petting and eventually killing Curley’s wife.
George finds out from Candy what Lennie has done.
George is conflicted about what to do with Lennie (who has run off to their hiding spot by the river). He doesn’t want to have Lennie locked up like "an animal," but he doesn’t want Curley to shoot Lennie in the guts, either.
George and Candy realize that the dream of the farm is over.
George secretly steals Carlson’s gun and tells the men that Lennie has gone south.
George goes north to the river and finds Lennie.
George tells Lennie the story of the dream farm again.
While George is narrating, he shoots Lennie in the back of the head.
When the other men arrive, George pretends that Lennie had Carlson’s gun.
George goes off for a (very stiff) drink with Slim.