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One of the major themes in Cutting for Stone is that life is full of pain and suffering. Oof.
Well, the good news is that it manages to be a pretty uplifting story, anyway. No, suffering can't be avoided, but the characters in this novel just find a way to live with it. The key is in compassion: in fact, a number of characters say that they believe that relieving others' suffering is their purpose in life.
There's plenty of suffering to relieve, too, considering that the novel takes place in a hospital.
In Cutting for Stone, suffering is a part of the human condition and should be embraced.
The characters in Cutting for Stone dedicate their lives to fighting suffering.